Thousands of Palestinians protested for the fourth Friday this month against the US president's decision to recognise Jerusalem as Israel's capital.
Protesters marched on the streets in Gaza and the West Bank, chanting “Death to America, death to Israel, and death to Trump”.
According to local health officials at least 50 Palestinians have been injured by live fire by Israeli troops.
Mr Trump's decision has been widely condemned internationally, with the UN General Assembly on passing resolution December 21, condemning the US decision, with 128 states voting in favour of the resolution and 9 against. Thirty-five states abstained, 21 did not vote.